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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ldt</journal-id><journal-title-group><journal-title xml:lang="ru">Лучевая диагностика и терапия</journal-title><trans-title-group xml:lang="en"><trans-title>Diagnostic radiology and radiotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-5343</issn><publisher><publisher-name>Baltic Medical Education Center</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22328/2079-5343-2024-15-4-87-97</article-id><article-id custom-type="elpub" pub-id-type="custom">ldt-1053</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Популяционное исследование расширения легочного ствола у населения г. Москвы на основе автоматизированного анализа результатов лучевых исследований</article-title><trans-title-group xml:lang="en"><trans-title>Investigation of pulmonary artery dilation in the population of Moscow using automated analysis of radiological examination results</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4485-2638</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соловьёв</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Solovev</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Соловьёв Александр Владимирович – младший научный сотрудник отдела стандартизации и контроля качества государственного бюджетного учреждения здравоохранения города Москвы; врач-рентгенолог государственного бюджетного учреждения здравоохранения города Москвы</p><p>127051, Москва, ул. Петровка, д. 24, стр. 1;</p><p>119049, Москва, пер. 4-й Добрынинский, д. 1/9</p></bio><bio xml:lang="en"><p>Alexander V. Solovev – Junior Researcher at the Department of Standardization and Quality Control Scientific and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Department of Health</p><p>127051, Moscow, st. Petrovka, 24, building 1;</p><p>119049, Moscow, per. 4th Dobryninsky, 1/9</p></bio><email xlink:type="simple">atlantis.92@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0208-5218</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilev</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильев Юрий Александрович – кандидат медицинских наук, директор государственного бюджетного учреждения здравоохранения города Москвы</p><p>127051, Москва, ул. Петровка, д. 24, стр. 1</p></bio><bio xml:lang="en"><p>Yuriy A. Vasilev – Cand. of Sci. (Med.), Director</p><p>127051, Moscow, st. Petrovka, 24, building 1</p></bio><email xlink:type="simple">VasilevYA1@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5649-2193</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синицын</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinitsyn</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Синицын Валентин Евгеньевич – доктор медицинских наук, профессор, руководитель по развитию международного научного партнерства государственного бюджетного учреждения здравоохранения города Москвы; заведующий кафедрой лучевой диагностики и терапии факультета фундаментальной медицины федерального государственного бюджетного образовательного учреждения высшего образования</p><p>127051, Москва, ул. Петровка, д. 24, стр. 1;</p><p> </p></bio><bio xml:lang="en"><p>Valentin E. Sinitsyn – Dr. of Sci. (Med.), Professor, Head of the Department of Radiation Diagnostics and Therapy of the Faculty of Fundamental Medicine</p><p>127051, Moscow, st. Petrovka, 24, building 1</p></bio><email xlink:type="simple">vsini@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2990-7736</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Владзимирский</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vladzymyrskyy</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владзимирский Антон Вячеславович – доктор медицинских наук, заместитель директора по научной работе государственного бюджетного учреждения здравоохранения города Москвы</p><p>127051, Москва, ул. Петровка, д. 24, стр. 1</p></bio><bio xml:lang="en"><p>Anton V. Vladzymyrskyy – Dr. of Sci. (Med.), Deputy Director for Scientific Work Scientific</p><p>127051, Moscow, st. Petrovka, 24, building 1</p></bio><email xlink:type="simple">VladzimirskijAV@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-8470-223X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванова Галина Владимировна – младший научный сотрудник отдела стандартизации и контроля качества государственного бюджетного учреждения здравоохранения города Москвы</p><p>127051, Москва, ул. Петровка, д. 24, стр. 1</p></bio><bio xml:lang="en"><p>Galina V. Ivanova – Junior Researcher at the Department of Standardization and Quality Control Scientific</p><p>127051, Moscow, st. Petrovka, 24, building 1</p></bio><email xlink:type="simple">IvanovaGV13@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-практический клинический центр диагностики и телемедицинских технологий; Морозовская детская городская клиническая больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research and Practical Clinical Center for Diagnostics and Telemedicine ; Morozov Children’s Municipal Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-практический клинический центр диагностики и телемедицинских технологий</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research and Practical Clinical Center for Diagnostics and Telemedicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Научно-практический клинический центр диагностики и телемедицинских технологий; Московский государственный университет имени М. В. Ломоносова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research and Practical Clinical Center for Diagnostics and Telemedicine ; Lomonosov Moscow State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>29</day><month>01</month><year>2025</year></pub-date><volume>15</volume><issue>4</issue><fpage>87</fpage><lpage>97</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Соловьёв А.В., Васильев Ю.А., Синицын В.Е., Владзимирский А.В., Иванова Г.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Соловьёв А.В., Васильев Ю.А., Синицын В.Е., Владзимирский А.В., Иванова Г.В.</copyright-holder><copyright-holder xml:lang="en">Solovev A.V., Vasilev Y.A., Sinitsyn V.E., Vladzymyrskyy A.V., Ivanova G.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://radiag.bmoc-spb.ru/jour/article/view/1053">https://radiag.bmoc-spb.ru/jour/article/view/1053</self-uri><abstract><sec><title>ВВЕДЕНИЕ</title><p>ВВЕДЕНИЕ: В современной клинической практике диагностика и мониторинг состояния легочного ствола являются важными компонентами заботы о пациентах с сердечно-сосудистыми и респираторными заболеваниями. В Российской Федерации пока имеется ограниченное количество эпидемиологических данных, касающихся распространенности дилатации легочного ствола, частоты выявления легочной гипертензии и ее причин.</p><p>Настоящее исследование направлено на заполнение этого пробела, предоставляя популяционные данные о распространенности дилатации ствола легочной артерии в городе Москве. Данная работа стремится предложить обоснованную оценку патологии, охватывающую как основные характеристики, так и особенности воздействия различных факторов, таких как возраст и пол, используя передовые технологии искусственного интеллекта.</p></sec><sec><title>ЦЕЛЬ</title><p>ЦЕЛЬ: Исследование распространенности расширения легочного ствола в городе Москве по данным компьютерной томографии органов грудной клетки с автоматическим анализом, выполненным с помощью технологии искусственного интеллекта.</p></sec><sec><title>МАТЕРИАЛЫ И МЕТОДЫ</title><p>МАТЕРИАЛЫ И МЕТОДЫ: Исследование включает анализ обширного объема КТ-исследований органов грудной клетки, проведенных в период с октября 2022 г. по февраль 2023 г. Общая выборка исследования составила 125 878 пациентов. Для автоматического выявления признаков дилатации легочного ствола применялись технологии искусственного интеллекта.</p></sec><sec><title>РЕЗУЛЬТАТЫ</title><p>РЕЗУЛЬТАТЫ: Анализ данных 125 878 КТ-исследований, включая 57 913 мужчин и 67 965 женщин, показал, что 34,4% пациентов (43 242 человека) имели признаки расширения легочного ствола. Среди них доля мужчин с данной патологией составила 35,6% (20 630 человек), а женщин – 33,3% (22 612 человек). Частота выявления патологии увеличивалась с возрастом, начиная с 14,8% среди молодых пациентов и достигая 62,7% среди пожилых. Распространенность расширения легочного ствола среди населения г. Москвы составила 794,7 случая на 100 000 человек.</p></sec><sec><title>ОБСУЖДЕНИЕ</title><p>ОБСУЖДЕНИЕ: На основании проведенного исследования делаются выводы о значимости расширения легочного ствола как предиктора легочной гипертензии. Отмечается важность ранней диагностики для предотвращения тяжелых осложнений, особенно у пациентов с хроническими заболеваниями легких. Была выявлена статистически значимая корреляция между патологией и полом, а также возрастной группой. Детальный анализ также выявил связь с возрастом и полом в контексте диаметра легочного ствола.</p></sec><sec><title>ЗАКЛЮЧЕНИЕ</title><p>ЗАКЛЮЧЕНИЕ: Исследование предоставило первые популяционные данные о распространенности дилатации легочного ствола в Москве. Результаты исследования могут служить основой для развития стратегий скрининга и подходов к лечению данной патологии.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>INTRODUCTION</title><p>INTRODUCTION: In modern clinical practice, the diagnosis establishment and monitoring of pulmonary arteries are important components of care for patients with cardiovascular and respiratory diseases. However, in Russia, there remains a limited amount of epidemiological data on the prevalence of pulmonary artery dilation, especially at the population level.</p><p>This study aims to fill this gap by providing population-based data on the prevalence of pulmonary artery dilation in the city of Moscow. With the help of advanced artificial intelligence technologies, this work seeks to offer a comprehensive assessment of the pathology, covering both its main characteristics and the effects of various factors such as age and gender.</p></sec><sec><title>OBJECTIVE</title><p>OBJECTIVE: To investigate the prevalence of pulmonary artery dilation in Moscow using the data from computed tomography (CT) scans of the chest analysed by means of an automatic artificial intelligence technology.</p></sec><sec><title>MATERIALS AND METHODS</title><p>MATERIALS AND METHODS: The study involved the analysis of a large volume of chest CT scans acquired from September 2022 to February 2023. The total study sample comprised 134,218 patients. Artificial intelligence technologies were applied for the automatic detection of signs of pulmonary artery dilation.</p></sec><sec><title>RESULTS</title><p>RESULTS: An analysis of 125,878 CT scans, including 57,913 men and 67,965 women, revealed that 34.4% of patients (43,242 individuals) showed signs of pulmonary artery dilation. Among them, the proportion of men with this pathology was 35.6% (20,630 individuals), while for women it was 33.3% (22,612 individuals). The prevalence of the pathology increased with age, starting at 14.8% among younger patients and reaching 62.7% among the elderly. The prevalence of pulmonary artery dilation among the population of Moscow was 794.7 cases per 100,000 people.</p></sec><sec><title>DISCUSSION</title><p>DISCUSSION: The results of this research allowed us to draw conclusions regarding the meaning of pulmonary artery dilation as a predictor of pulmonary hypertension. The results demonstrated a correlation between the frequency of pathology occurrence and gender and age groups, with a more pronounced association observed in women. Detailed analysis also revealed corellations of pulmonary artery diameter with age and gender.</p></sec><sec><title>CONCLUSION</title><p>CONCLUSION: The study provided the first population-based data on the prevalence of pulmonary artery dilation in Moscow. The importance of early diagnosis to prevent severe complications, especially in patients with chronic lung diseases, is emphasized. The study results can provide a basis for screening strategies and treatment approaches for this pathology.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>компьютерная томография</kwd><kwd>расширение легочного ствола</kwd><kwd>искусственный интеллект</kwd></kwd-group><kwd-group xml:lang="en"><kwd>computed tomography</kwd><kwd>pulmonary artery dilation</kwd><kwd>artificial intelligence</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hoeper M.M., Humbert M., Souza R. et al. A global view of pulmonary hypertension // Lancet Respir. Med. Elsevier. 2016. Vol. 4, No. 4. P. 306–322. doi: 10.1016/S2213-2600(15)00543-3.</mixed-citation><mixed-citation xml:lang="en">Hoeper M.M., Humbert M., Souza R. et al. A global view of pulmonary hypertension // Lancet Respir. Med. Elsevier. 2016. Vol. 4, No. 4. P. 306–322. doi: 10.1016/S2213-2600(15)00543-3.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Galiè N., Humbert M., Vachiery J.L. et al. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endor // Eur. Respir. J. 2015. Vol. 46, No. 4. P. 903–975. doi: 10.1183/13993003.51032-2015.</mixed-citation><mixed-citation xml:lang="en">Galiè N., Humbert M., Vachiery J.L. et al. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endor // Eur. Respir. J. 2015. Vol. 46, No. 4. P. 903–975. doi: 10.1183/13993003.51032-2015.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Humbert M., Kovacs G., Hoeper M.M. et al. 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: Developed by the task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS). Endorsed by the International Society for Heart and Lung Transplantation (ISHLT) and the European Reference Network on rare respiratory diseases (ERN-LUNG) // Eur. Heart J. Oxford Academic, 2023. Vol. 44, No. 15. P. 1312–1312. https://doi.org/10.1093/eurheartj/ehad005.</mixed-citation><mixed-citation xml:lang="en">Humbert M., Kovacs G., Hoeper M.M. et al. 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: Developed by the task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS). Endorsed by the International Society for Heart and Lung Transplantation (ISHLT) and the European Reference Network on rare respiratory diseases (ERN-LUNG) // Eur. Heart J. Oxford Academic, 2023. Vol. 44, No. 15. P. 1312–1312. https://doi.org/10.1093/eurheartj/ehad005.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Gabbay E., Fraser J., McNeil K. Review of bosentan in the management of pulmonary arterial hypertension // Vascular health and risk management. 2007. Vol. 3, 6. Р. 887–900. https://doi.org/10.2147/vhrm.s12187426.</mixed-citation><mixed-citation xml:lang="en">Gabbay E., Fraser J., McNeil K. Review of bosentan in the management of pulmonary arterial hypertension // Vascular health and risk management. 2007. Vol. 3, 6. Р. 887–900. https://doi.org/10.2147/vhrm.s12187426.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Chazova I.E., Martynyuk T.V., Valieva Z.S. et al. Eurasian Clinical Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension // Eurasian Journal of Cardiology. 2020. No. 1. P. 78–122. https://doi.org/10.38109/2225-1685-2020-1-78-122.</mixed-citation><mixed-citation xml:lang="en">Chazova I.E., Martynyuk T.V., Valieva Z.S. et al. Eurasian Clinical Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension // Eurasian Journal of Cardiology. 2020. No. 1. P. 78–122. https://doi.org/10.38109/2225-1685-2020-1-78-122.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Aliev A.F., Kudryavtsev N.D., Petraikin A.V. et al. Changing of pulmonary artery diameter in accordance with severity of COVID-19 (assessment based on non-contrast computer tomography) // Digit. Diagnostics. Eco-Vector LLC, 2021. Vol. 2, No. 3. P. 249–260. doi: 10.17816/DD76726.</mixed-citation><mixed-citation xml:lang="en">Aliev A.F., Kudryavtsev N.D., Petraikin A.V. et al. Changing of pulmonary artery diameter in accordance with severity of COVID-19 (assessment based on non-contrast computer tomography) // Digit. Diagnostics. Eco-Vector LLC, 2021. Vol. 2, No. 3. P. 249–260. doi: 10.17816/DD76726.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Chuchalin A.G., Khaltaev N., Antonov N.S. et al. Chronic respiratory diseases and risk factors in 12 regions of the Russian Federation // Int. J. Chron. Obstruct. Pulmon. Dis. Dove Press. 2014. Vol. 9, No. 1. P. 963–974. doi: 10.2147/COPD.S67283.</mixed-citation><mixed-citation xml:lang="en">Chuchalin A.G., Khaltaev N., Antonov N.S. et al. Chronic respiratory diseases and risk factors in 12 regions of the Russian Federation // Int. J. Chron. Obstruct. Pulmon. Dis. Dove Press. 2014. Vol. 9, No. 1. P. 963–974. doi: 10.2147/COPD.S67283.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Lewis G., Hoey E.T., Reynolds J.H. et al. Multi-detector CT assessment in pulmonary hypertension: techniques, systematic approach to interpretation and key findings // Quant. Imaging Med. Surg. AME Publications. 2015. Vol. 5, No. 3. P. 423. doi: 10.3978/j.issn.2223-4292.2015.01.05.</mixed-citation><mixed-citation xml:lang="en">Lewis G., Hoey E.T., Reynolds J.H. et al. Multi-detector CT assessment in pulmonary hypertension: techniques, systematic approach to interpretation and key findings // Quant. Imaging Med. Surg. AME Publications. 2015. Vol. 5, No. 3. P. 423. doi: 10.3978/j.issn.2223-4292.2015.01.05.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Truong Q.A., Massaro J.M., Rogers I.S. et al. Reference Values for Normal Pulmonary Artery Dimensions by Noncontrast Cardiac Computed Tomography // Circ. Cardiovasc. Imaging. 2012. Vol. 5, No. 1. P. 147–154. doi: 10.1161/CIRCIMAGING.111.968610.</mixed-citation><mixed-citation xml:lang="en">Truong Q.A., Massaro J.M., Rogers I.S. et al. Reference Values for Normal Pulmonary Artery Dimensions by Noncontrast Cardiac Computed Tomography // Circ. Cardiovasc. Imaging. 2012. Vol. 5, No. 1. P. 147–154. doi: 10.1161/CIRCIMAGING.111.968610.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Gusev A.V., Vladzymyrskyy A.V., Sharova D.E. et al. Evolution of research and development in the field of artificial intelligence technologies for healthcare in the Russian Federation: results of 2021 // Digit. Diagnostics. 2022. Vol. 3, No. 3. doi: 10.17816/DD107367.</mixed-citation><mixed-citation xml:lang="en">Gusev A.V., Vladzymyrskyy A.V., Sharova D.E. et al. Evolution of research and development in the field of artificial intelligence technologies for healthcare in the Russian Federation: results of 2021 // Digit. Diagnostics. 2022. Vol. 3, No. 3. doi: 10.17816/DD107367.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Morozov S.P., Vladzymyrskyy A.V., Shulkin I.M. et al. Feasibility of using artificial intelligence in radiology (first year of Moscow experiment on computer vision) // Doctor and information technology. 2022. No. 1. doi: 10.25881/18110193_2022_1_12.</mixed-citation><mixed-citation xml:lang="en">Morozov S.P., Vladzymyrskyy A.V., Shulkin I.M. et al. Feasibility of using artificial intelligence in radiology (first year of Moscow experiment on computer vision) // Doctor and information technology. 2022. No. 1. doi: 10.25881/18110193_2022_1_12.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Morozov S.P., Gavrilov A.V., Arkhipov I.V. et al. Effect of artificial intelligence technologies on the CT scan interpreting time in COVID-19 patients in inpatient setting // Profil. Meditsina. 2022. Vol. 25, No. 1. doi: 10.17116/profmed20222501114.</mixed-citation><mixed-citation xml:lang="en">Morozov S.P., Gavrilov A.V., Arkhipov I.V. et al. Effect of artificial intelligence technologies on the CT scan interpreting time in COVID-19 patients in inpatient setting // Profil. Meditsina. 2022. Vol. 25, No. 1. doi: 10.17116/profmed20222501114.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Maslennikova G.Y., Oganov R.G. Prevention of noncommunicable diseases as an opportunity to increase life expectancy and healthy longevity // Cardiovasc. Ther. Prev. 2019. Vol. 18, No. 2. doi: 10.15829/1728-8800-2019-2-5-12.</mixed-citation><mixed-citation xml:lang="en">Maslennikova G.Y., Oganov R.G. Prevention of noncommunicable diseases as an opportunity to increase life expectancy and healthy longevity // Cardiovasc. Ther. Prev. 2019. Vol. 18, No. 2. doi: 10.15829/1728-8800-2019-2-5-12.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Zouk A.N., Gulati S., Xing D. et al. Pulmonary artery enlargement is associated with pulmonary hypertension and decreased survival in severe cystic fibrosis: A cohort study // PLoS One. 2020. Vol. 15, No. 2. doi: 10.1371/journal.pone.0229173.</mixed-citation><mixed-citation xml:lang="en">Zouk A.N., Gulati S., Xing D. et al. Pulmonary artery enlargement is associated with pulmonary hypertension and decreased survival in severe cystic fibrosis: A cohort study // PLoS One. 2020. Vol. 15, No. 2. doi: 10.1371/journal.pone.0229173.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Erratum: 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. The joint task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ER) // European Respiratory Journal. 2015. Vol. 46, No. 6. doi: 10.1093/eurheartj/ehv317.</mixed-citation><mixed-citation xml:lang="en">Erratum: 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. The joint task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ER) // European Respiratory Journal. 2015. Vol. 46, No. 6. doi: 10.1093/eurheartj/ehv317.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Lõpez-Campos J.L., Tan W., Soriano J.B. Global burden of COPD // Respirology. 2016. Vol. 21, No. 1. doi: 10.1111/resp.12660.</mixed-citation><mixed-citation xml:lang="en">Lõpez-Campos J.L., Tan W., Soriano J.B. Global burden of COPD // Respirology. 2016. Vol. 21, No. 1. doi: 10.1111/resp.12660.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">McGhan R., Radcliff T., Fish R. et al. Predictors of rehospitalization and death after a severe exacerbation of COPD // Chest. 2007. Vol. 132, No. 6. doi: 10.1378/chest.06-3018.</mixed-citation><mixed-citation xml:lang="en">McGhan R., Radcliff T., Fish R. et al. Predictors of rehospitalization and death after a severe exacerbation of COPD // Chest. 2007. Vol. 132, No. 6. doi: 10.1378/chest.06-3018.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Gologanu D., Stanescu C., Bogdan M.A. Pulmonary hypertension secondary to chronic obstructive pulmonary disease // Rom. J. Intern. Med. 2012. Vol. 50, No. 4. P. 259–268.</mixed-citation><mixed-citation xml:lang="en">Gologanu D., Stanescu C., Bogdan M.A. Pulmonary hypertension secondary to chronic obstructive pulmonary disease // Rom. J. Intern. Med. 2012. Vol. 50, No. 4. P. 259–268.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Arcasoy S.M., Christie J.D., Ferrari V.A. et al. Echocardiographic assessment of pulmonary hypertension in patients with advanced lung disease // Am. J. Respir. Crit. Care Med. 2003. Vol. 167, No. 5. doi: 10.1164/rccm.200210-1130OC.</mixed-citation><mixed-citation xml:lang="en">Arcasoy S.M., Christie J.D., Ferrari V.A. et al. Echocardiographic assessment of pulmonary hypertension in patients with advanced lung disease // Am. J. Respir. Crit. Care Med. 2003. Vol. 167, No. 5. doi: 10.1164/rccm.200210-1130OC.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Mandras S.A., Mehta H.S., Vaidya A. Pulmonary Hypertension: A Brief Guide for Clinicians // Mayo Clin. Proc. 2020. Vol. 95, No. 9. doi: 10.1016/j.mayocp.2020.04.039.</mixed-citation><mixed-citation xml:lang="en">Mandras S.A., Mehta H.S., Vaidya A. Pulmonary Hypertension: A Brief Guide for Clinicians // Mayo Clin. Proc. 2020. Vol. 95, No. 9. doi: 10.1016/j.mayocp.2020.04.039.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Iyer A.S., Wells J.M., Vishin S. et al. CT scan-measured pulmonary artery to aorta ratio and echocardiography for detecting pulmonary hypertension in severe COPD // Chest. 2014. Vol. 145, No. 4. doi: 10.1378/chest.13-1422.</mixed-citation><mixed-citation xml:lang="en">Iyer A.S., Wells J.M., Vishin S. et al. CT scan-measured pulmonary artery to aorta ratio and echocardiography for detecting pulmonary hypertension in severe COPD // Chest. 2014. Vol. 145, No. 4. doi: 10.1378/chest.13-1422.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">LaFon D.C., Bhatt S.P., Labaki W.W. et al. Pulmonary artery enlargement and mortality risk in moderate to severe COPD: Results from COPDGene // Eur. Respir. J. 2020. Vol. 55, No. 2. doi: 10.1183/13993003.01812-2019.</mixed-citation><mixed-citation xml:lang="en">LaFon D.C., Bhatt S.P., Labaki W.W. et al. Pulmonary artery enlargement and mortality risk in moderate to severe COPD: Results from COPDGene // Eur. Respir. J. 2020. Vol. 55, No. 2. doi: 10.1183/13993003.01812-2019.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Wells J.M., Washko G.R., Han M.K. et al. Pulmonary arterial enlargement and acute exacerbations of COPD // N. Engl. J. Med. 2012. Vol. 367, No. 10. doi: 10.1056/NEJMoa1203830.</mixed-citation><mixed-citation xml:lang="en">Wells J.M., Washko G.R., Han M.K. et al. Pulmonary arterial enlargement and acute exacerbations of COPD // N. Engl. J. Med. 2012. Vol. 367, No. 10. doi: 10.1056/NEJMoa1203830.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Chen H., Shu T., Wang L. et al. Pulmonary artery enlargement predicts poor survival in patients with COPD: A meta-analysis // Pulm. Circ. 2022. Vol. 12, No. 3. doi: 10.1002/pul2.12099.</mixed-citation><mixed-citation xml:lang="en">Chen H., Shu T., Wang L. et al. Pulmonary artery enlargement predicts poor survival in patients with COPD: A meta-analysis // Pulm. Circ. 2022. Vol. 12, No. 3. doi: 10.1002/pul2.12099.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Terzikhan N., Bos D., Lahousse L. et al. Pulmonary artery to aorta ratio and risk of all-cause mortality in the general population: The Rotterdam Study // Eur. Respir. J. 2017. Vol. 49, No. 6. doi: 10.1183/13993003.02168-2016.</mixed-citation><mixed-citation xml:lang="en">Terzikhan N., Bos D., Lahousse L. et al. Pulmonary artery to aorta ratio and risk of all-cause mortality in the general population: The Rotterdam Study // Eur. Respir. J. 2017. Vol. 49, No. 6. doi: 10.1183/13993003.02168-2016.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Wade R.C., Simmons J.P., Boueiz A. et al. Pulmonary artery enlargement is associated with exacerbations and mortality in ever-smokers with preserved ratio impaired spirometry // Am. J. Respir. Crit. Care Med. 2021. Vol. 204, No. 4. doi: 10.1164/rccm.202103-0619LE.</mixed-citation><mixed-citation xml:lang="en">Wade R.C., Simmons J.P., Boueiz A. et al. Pulmonary artery enlargement is associated with exacerbations and mortality in ever-smokers with preserved ratio impaired spirometry // Am. J. Respir. Crit. Care Med. 2021. Vol. 204, No. 4. doi: 10.1164/rccm.202103-0619LE.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Zhu Q.Q., Gong T., Huang G.Q. et al. Pulmonary artery trunk enlargement on admission as a predictor of mortality in in-hospital patients with COVID-19 // Jpn. J. Radiol. Springer Japan. 2021. Vol. 39, No. 6. P. 589–597. doi: 10.1007/s11604-021-01094-9.</mixed-citation><mixed-citation xml:lang="en">Zhu Q.Q., Gong T., Huang G.Q. et al. Pulmonary artery trunk enlargement on admission as a predictor of mortality in in-hospital patients with COVID-19 // Jpn. J. Radiol. Springer Japan. 2021. Vol. 39, No. 6. P. 589–597. doi: 10.1007/s11604-021-01094-9.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Nakanishi R., Rana J.S., Shalev A. et al. Mortality risk as a function of the ratio of pulmonary trunk to ascending aorta diameter in patients with suspected coronary artery disease // Am. J. Cardiol. 2013. Vol. 111, No. 9. doi: 10.1016/j.amjcard.2013.01.266.</mixed-citation><mixed-citation xml:lang="en">Nakanishi R., Rana J.S., Shalev A. et al. Mortality risk as a function of the ratio of pulmonary trunk to ascending aorta diameter in patients with suspected coronary artery disease // Am. J. Cardiol. 2013. Vol. 111, No. 9. doi: 10.1016/j.amjcard.2013.01.266.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Solovev A.V., Vasilev Y.A., Sinitsyn V.E. et al. Improving aortic aneurysm detection with artificial intelligence based on chest computed tomography data // Digital Diagnostics. 2024. Vol. 5, Nо. 1. P. 29–40. doi: 10.17816/DD569388.</mixed-citation><mixed-citation xml:lang="en">Solovev A.V., Vasilev Y.A., Sinitsyn V.E. et al. Improving aortic aneurysm detection with artificial intelligence based on chest computed tomography data // Digital Diagnostics. 2024. Vol. 5, Nо. 1. P. 29–40. doi: 10.17816/DD569388.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Vasiliev Yu.A., Bobrovskaya T.M., Arzamasov K.M. et al. Fundamental principles of standardization and systematization of information about data sets for machine learning in medical diagnostics // Manager of Healthcare. 2023. No. 4. P. 28–41. doi: 10.21045/1811–0185-2023-4-28-41.</mixed-citation><mixed-citation xml:lang="en">Vasiliev Yu.A., Bobrovskaya T.M., Arzamasov K.M. et al. Fundamental principles of standardization and systematization of information about data sets for machine learning in medical diagnostics // Manager of Healthcare. 2023. No. 4. P. 28–41. doi: 10.21045/1811–0185-2023-4-28-41.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
