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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ldt</journal-id><journal-title-group><journal-title xml:lang="ru">Лучевая диагностика и терапия</journal-title><trans-title-group xml:lang="en"><trans-title>Diagnostic radiology and radiotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-5343</issn><publisher><publisher-name>Baltic Medical Education Center</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22328/2079-5343-2016-3-5-14</article-id><article-id custom-type="elpub" pub-id-type="custom">ldt-145</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РЕДАКЦИОННАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EDITORIAL</subject></subj-group></article-categories><title-group><article-title>КЛИНИКО-ПАТОФИЗИОЛОГИЧЕСКИЕ ОСОБЕННОСТИ ПОВРЕЖДЕНИЯ БЕЛОГО ВЕЩЕСТВА ГОЛОВНОГО МОЗГА У НЕДОНОШЕННЫХ ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>CLINICAL AND PATHOLOGICAL FEATURES OF WHITE MATTER DAMAGE IN PRETERM BABIES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мелашенко</surname><given-names>Татьяна Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Melashenko</surname><given-names>T. V.</given-names></name></name-alternatives><email xlink:type="simple">melashenkotat@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поздняков</surname><given-names>Александр Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Pozdnykov</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тащилкин</surname><given-names>Алексей Иванович</given-names></name><name name-style="western" xml:lang="en"><surname>Taschilkin</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский государственный педиатрический медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Petersburg State Pediatric Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>01</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>3</issue><fpage>5</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мелашенко Т.В., Поздняков А.В., Тащилкин А.И., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Мелашенко Т.В., Поздняков А.В., Тащилкин А.И.</copyright-holder><copyright-holder xml:lang="en">Melashenko T.V., Pozdnykov A.V., Taschilkin A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://radiag.bmoc-spb.ru/jour/article/view/145">https://radiag.bmoc-spb.ru/jour/article/view/145</self-uri><abstract><p>Отдаленные неврологические нарушения, наблюдаемые у недоношенных детей, в основном определяются повреждением незрелого белого вещества. Выделены формы повреждения церебрального белого вещества у недоношенных детей, в том числе бескистозные. Малые формы повреждения белого вещества являются распространенной патологией головного мозга среди недоношенных новорожденных с малым сроком гестации (менее 28 недель). Ключевую роль в повреждении церебрального белого вещества у недоношенных новорожденных играют выраженность миелинизации церебральных структур, изменение способности клеток головного мозга к продолжению пролиферации и миграции при воздействии повреждающих факторов, активность клеток нейроглии.</p></abstract><trans-abstract xml:lang="en"><p>Long-term neurological sequels in preterm babies in great cases are determinated by injury of immature cerebral white matter. There are several known forms of the white matter injure including noncystes forms. The noncystes forms of the white matter injury are general cerebral pathology in the preterm babies with low gestation age (born before 28 weeks). The main causes of the white matter damage related with extent of the cerebral myelination, the modification of cerebral immature cells, glial cells ability to prolong proliferations, migration and activity for exposed damaging factors as well.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>недоношенные новорожденные</kwd><kwd>повреждение белого вещества головного мозга</kwd><kwd>паттерны</kwd><kwd>preterm babies</kwd><kwd>damage of cerebral white matter</kwd><kwd>pettern</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Blencowe Н., Cousens S., Oestergaard M. Z. et al. National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications // Lancet.- 2012.- Vol. 379.- Р. 2162-2172.</mixed-citation><mixed-citation xml:lang="en">Blencowe Н., Cousens S., Oestergaard M. 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