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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ldt</journal-id><journal-title-group><journal-title xml:lang="ru">Лучевая диагностика и терапия</journal-title><trans-title-group xml:lang="en"><trans-title>Diagnostic radiology and radiotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-5343</issn><publisher><publisher-name>Baltic Medical Education Center</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22328/2079-5343-2016-4-52-56</article-id><article-id custom-type="elpub" pub-id-type="custom">ldt-180</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>ОПТИМИЗАЦИЯ МУЛЬТИСПИРАЛЬНОЙ КОМПЬЮТЕРНОЙ ТОМОГРАФИИ ГРУДИ У БОЛЬНЫХ РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫ</article-title><trans-title-group xml:lang="en"><trans-title>OPTIMIZATION OF MULTISPIRAL COMPUTED TOMOGRAPHY OF THE CHEST IN BREAST CANCER PATIENTS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Буровик</surname><given-names>Илья Александрович</given-names></name><name name-style="western" xml:lang="en"><surname>Burovik</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">burovick_ilya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мёлдо</surname><given-names>Анна Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Méldo</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">anna.meldo@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мищенко</surname><given-names>Андрей Владимирович</given-names></name><name name-style="western" xml:lang="en"><surname>Mishchenko</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">dr.mishchenko@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулева</surname><given-names>Светлана Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Kulyeva</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">kulevadoc@yandex.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Косичкина</surname><given-names>Анастасия Борисовна</given-names></name><name name-style="western" xml:lang="en"><surname>Kosichkina</surname><given-names>A. B.</given-names></name></name-alternatives><email xlink:type="simple">akosichkina@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ онкологии им. Н. Н. Петрова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N. N. Petrov Oncology Research Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Санкт-Петербургский клинический научно-практический центр специализированных видов медицинской помощи (онкологический)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Petersburg Scientific Practical Center of Specialized Kinds of Medical Care (Oncological)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>НИИ онкологии им. Н. Н. Петрова; Научно-клинический и образовательный Центр «Лучевая диагностика и ядерная медицина»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N. N. Petrov Oncology Research Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБОУ ВПО СПбГПМУ МЗ РФ; ФГБУ «НИИ онкологии им. Н. Н. Петрова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N. N. Petrov Oncology Research Institute</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>03</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>4</issue><fpage>52</fpage><lpage>56</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Буровик И.А., Мёлдо А.А., Мищенко А.В., Кулева С.А., Косичкина А.Б., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Буровик И.А., Мёлдо А.А., Мищенко А.В., Кулева С.А., Косичкина А.Б.</copyright-holder><copyright-holder xml:lang="en">Burovik I.A., Méldo A.A., Mishchenko A.V., Kulyeva S.A., Kosichkina A.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://radiag.bmoc-spb.ru/jour/article/view/180">https://radiag.bmoc-spb.ru/jour/article/view/180</self-uri><abstract><p>Монофазная МСКТ груди с контрастным усилением у больных раком молочной железы не позволяет ответить на все диагностические вопросы, вместе с тем многофазное исследование сопровождается значительной лучевой нагрузкой на пациента. Актуальность мер, направленных на снижение дозы облучения, обусловливает целесообразность применения венозно-артериального контрастирования при МСКТ груди у больных раком молочной железы. При сравнении нативной, артериальной и венозно-артериальной фаз установлено статистически значимое повышение плотности опухоли молочной железы при венозно-артериальном сканировании. Контрастное усиление в крупных сосудах в венозно-артериальную и артериальную фазы сканирования было практически идентичным. Таким образом, методика венозно-артериального МСКТ-сканирования обеспечивает значимое увеличение рентгеновской плотности карциномы молочной железы до 2 раз по сравнению с соответствующим значением в артериальную фазу исследования с сохранением целевых величин контрастного усиления легочного ствола и аорты, обеспечивая уменьшение дозы облучения пациента.</p></abstract><trans-abstract xml:lang="en"><p>Monophasic MSCT of chest in patients with breast cancer unable to answer all diagnostic questions. However, multiphasic MSCT is associated with a significant radiation dose. In order to reduce radiation exposure for patients with breast cancer venous-arterial phase of MSCT can be used. Native, arterial and venous-arterial phases of ceMSCT of chest were compared. There was statistically significant increase of breast tumor x-ray density in venous-arterial scan (up to 2 times compared with the corresponding value in arterial phase of the study). Contrast enhancement in large vessels in venous-arterial and arterial phase scans was almost similar. Thus, the technique of venous-arterial MDCT provides a significant increase in x-ray density of breast carcinoma, keeps suitable values of contrast enhancement of the pulmonary trunk and aorta and reduces radiation dose.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лучевая нагрузка при КТ</kwd><kwd>снижение дозы облучения</kwd><kwd>КТ при раке молочной железы</kwd><kwd>венозно-артериальное сканирование</kwd><kwd>CT radiation dose</kwd><kwd>reduction of radiation dose</kwd><kwd>CT in breast cancer</kwd><kwd>venous-arterial contrast scanning</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Raptopoulos V., Baum J. K., Hochman M. et al. High resolution CT mammography of surgical biopsy specimens // J. Comput. Assist. Tomogr.- 1996.- Vol. 20, № 2.- Р. 179-184.</mixed-citation><mixed-citation xml:lang="en">Raptopoulos V., Baum J. K., Hochman M. et al. High resolution CT mammography of surgical biopsy specimens // J. Comput. Assist. Tomogr.- 1996.- Vol. 20, № 2.- Р. 179-184.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Nakahara H., Namba K., Wakamatsu H. et al. Extension of breast cancer: comparison of CT and MRI // Radiat Med.- 2002.- Vol. 20.- Р 17-23.</mixed-citation><mixed-citation xml:lang="en">Nakahara H., Namba K., Wakamatsu H. et al. Extension of breast cancer: comparison of CT and MRI // Radiat Med.- 2002.- Vol. 20.- Р 17-23.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Shimauchi A., Yamada T., Sato A. et al. Comparison of MDCT and MRI for evaluating the intraductal component of breast cancer // AJR Am. J. Roentgenol.- 2006.- Vol. 187.- Р 322-329.</mixed-citation><mixed-citation xml:lang="en">Shimauchi A., Yamada T., Sato A. et al. Comparison of MDCT and MRI for evaluating the intraductal component of breast cancer // AJR Am. J. Roentgenol.- 2006.- Vol. 187.- Р 322-329.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Uematsu T., Yuen S., Kasami M., Uchida Y. Comparison of magnetic resonance imaging, multidetector row computed tomography, ultrasonography, and mammography for tumor extension of breast cancer // Breast Cancer Res. Treat.- 2008.- Vol. 112.- Р 461-474.</mixed-citation><mixed-citation xml:lang="en">Uematsu T., Yuen S., Kasami M., Uchida Y. Comparison of magnetic resonance imaging, multidetector row computed tomography, ultrasonography, and mammography for tumor extension of breast cancer // Breast Cancer Res. Treat.- 2008.- Vol. 112.- Р 461-474.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Neal C. H., Yilmaz Z. N., Noroozian M. et al. Imaging of breast cancer-related changes after surgical therapy // AJR Am. J. Roentgenol.- 2014.- Vol. 202, № 2.- Р 262-272.</mixed-citation><mixed-citation xml:lang="en">Neal C. H., Yilmaz Z. N., Noroozian M. et al. Imaging of breast cancer-related changes after surgical therapy // AJR Am. J. Roentgenol.- 2014.- Vol. 202, № 2.- Р 262-272.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Yilmaz Z. N., Neal C. H., Noroozian M. et al. Imaging of breast cancer-related changes after nonsurgical therapy // AJR Am. J. Roentgenol.- 2014.- Vol. 202, № 3.- Р 675-683.</mixed-citation><mixed-citation xml:lang="en">Yilmaz Z. N., Neal C. H., Noroozian M. et al. Imaging of breast cancer-related changes after nonsurgical therapy // AJR Am. J. Roentgenol.- 2014.- Vol. 202, № 3.- Р 675-683.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Diekmann F., Diekmann S., Taupitz M. et al. Use of iodine-based contrast media in digital full-field mammography - initial experience // Rofo. Fortschr. Geb. Rontgenstr. Neuen Bildgeb. Verfahr.- 2003.- Vol. 175, № 3.- Р 342-345.</mixed-citation><mixed-citation xml:lang="en">Diekmann F., Diekmann S., Taupitz M. et al. Use of iodine-based contrast media in digital full-field mammography - initial experience // Rofo. Fortschr. Geb. Rontgenstr. Neuen Bildgeb. Verfahr.- 2003.- Vol. 175, № 3.- Р 342-345.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Jong R. A., Yaffe M. J., Skarpathiotakis M. et al. Contrast-enhanced digital mammography: Initial clinical experience // Radiology.- 2003.- Vol. 228, № 3.- Р 842-850.</mixed-citation><mixed-citation xml:lang="en">Jong R. A., Yaffe M. J., Skarpathiotakis M. et al. Contrast-enhanced digital mammography: Initial clinical experience // Radiology.- 2003.- Vol. 228, № 3.- Р 842-850.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Dromain C., Balleyguier C., Muller S. et al. Evaluation of tumor angiogenesis of breast carcinoma using contrast-enhanced digital mammography // Am. J. Roentgenol.- 2006.- Vol. 187, № 5.- P. 528-537.</mixed-citation><mixed-citation xml:lang="en">Dromain C., Balleyguier C., Muller S. et al. Evaluation of tumor angiogenesis of breast carcinoma using contrast-enhanced digital mammography // Am. J. Roentgenol.- 2006.- Vol. 187, № 5.- P. 528-537.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Diekmann F., Diekmann S., Jeunehomme F. et al. Digital mammography using iodine-based contrast media: initial clinical experience with dynamic contrastmedium enhancement // Invest. Radiol.- 2005.- Vol. 40, № 7.- Р 397-404.</mixed-citation><mixed-citation xml:lang="en">Diekmann F., Diekmann S., Jeunehomme F. et al. Digital mammography using iodine-based contrast media: initial clinical experience with dynamic contrastmedium enhancement // Invest. Radiol.- 2005.- Vol. 40, № 7.- Р 397-404.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Chen S. С., Carton A. K., Albert M. et al. Initial clinical experience with contrast-enhanced digital breast tomosynthesis // Acad. Radiol.- 2007.- Vol. 14, No. 2.- Р. 229-238.</mixed-citation><mixed-citation xml:lang="en">Chen S. С., Carton A. K., Albert M. et al. Initial clinical experience with contrast-enhanced digital breast tomosynthesis // Acad. Radiol.- 2007.- Vol. 14, No. 2.- Р. 229-238.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Lindfors K. K., Boone J. M., Nelson T. R. et al. Dedicated breast CT: Initial clinical experience // Radiology.- 2008.- Vol. 246, № 3.- P. 725-733.</mixed-citation><mixed-citation xml:lang="en">Lindfors K. K., Boone J. M., Nelson T. R. et al. Dedicated breast CT: Initial clinical experience // Radiology.- 2008.- Vol. 246, № 3.- P. 725-733.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Boone J. M. Breast CT: Its prospect for breast cancer screening and diagnosis, in Advances in breast imaging: Physics, Technology and Clinical Applications, Categorical Course in Diagnostic Radiology Physics. Giger edited by A. Karellas and M. L. Radiological Society of North America (RSNA), Oak Brook, IL, 2004.</mixed-citation><mixed-citation xml:lang="en">Boone J. M. Breast CT: Its prospect for breast cancer screening and diagnosis, in Advances in breast imaging: Physics, Technology and Clinical Applications, Categorical Course in Diagnostic Radiology Physics. Giger edited by A. Karellas and M. L. Radiological Society of North America (RSNA), Oak Brook, IL, 2004.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Lindfors K. K., Boone J. M., Newell M. S., D’Orsi C. J. Dedicated breast CT: the optimal cross sectional imaging solution // Radiol. Clin. North Am.- 2010.- Vol. 48, № 5.- Р 1043-1054.</mixed-citation><mixed-citation xml:lang="en">Lindfors K. K., Boone J. M., Newell M. S., D’Orsi C. J. Dedicated breast CT: the optimal cross sectional imaging solution // Radiol. Clin. North Am.- 2010.- Vol. 48, № 5.- Р 1043-1054.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Абдураимов А. Б. Применение КТ-маммографии в комплексной диагностике рецидива рака молочной железы // Медицинская визуализация.- 2010.- № 3.- С. 11-18.</mixed-citation><mixed-citation xml:lang="en">Абдураимов А. Б. Применение КТ-маммографии в комплексной диагностике рецидива рака молочной железы // Медицинская визуализация.- 2010.- № 3.- С. 11-18.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Абдураимов А. Б., Ветшев П. С., Терновой С. К., Араблинский А. В., Шехтер А. И. Мультиспиральная компьютерная томография в диагностике опухолей молочной железы (первые результаты) // Хирургия.- 2005.- № 2.- С. 12-17.</mixed-citation><mixed-citation xml:lang="en">Абдураимов А. Б., Ветшев П. С., Терновой С. К., Араблинский А. В., Шехтер А. И. Мультиспиральная компьютерная томография в диагностике опухолей молочной железы (первые результаты) // Хирургия.- 2005.- № 2.- С. 12-17.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Буровик И. А., Локшина А. А., Кулева С. А. Оптимизация методики мультиспиральной компьютерной томографии при динамическом наблюдении онкологических больных // Медицинская визуализация.- 2015.- № 2.- С. 129-134.</mixed-citation><mixed-citation xml:lang="en">Буровик И. А., Локшина А. А., Кулева С. А. Оптимизация методики мультиспиральной компьютерной томографии при динамическом наблюдении онкологических больных // Медицинская визуализация.- 2015.- № 2.- С. 129-134.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Семиглазов В. В., Топузов Э. Э. Рак молочной железы / под ред. В. Ф. Семиглазова.- М., Медпресс-информ, 2009.- 172 с.</mixed-citation><mixed-citation xml:lang="en">Семиглазов В. В., Топузов Э. Э. Рак молочной железы / под ред. В. Ф. Семиглазова.- М., Медпресс-информ, 2009.- 172 с.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Preston-Martin S., Pogoda J. M. Estimation of radiographic doses in a case-control study of acute myelogenous leukemia // Health Phys.- 2003.- Vol. 84.- Р 245-259.</mixed-citation><mixed-citation xml:lang="en">Preston-Martin S., Pogoda J. M. Estimation of radiographic doses in a case-control study of acute myelogenous leukemia // Health Phys.- 2003.- Vol. 84.- Р 245-259.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Berrington de Gonzalez A., Darby S. Risk of cancer from diagnostic X-rays: estimates for the UK and 14 other countries // Lancet.- 2004.- Vol. 363.- Р 345-351.</mixed-citation><mixed-citation xml:lang="en">Berrington de Gonzalez A., Darby S. Risk of cancer from diagnostic X-rays: estimates for the UK and 14 other countries // Lancet.- 2004.- Vol. 363.- Р 345-351.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
