ldtЛучевая диагностика и терапияDiagnostic radiology and radiotherapy2079-5343Baltic Medical Education Center10.22328/2079-5343-2018-4-39-43ldt-340Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL RESEARCHИЗМЕНЕНИЯ ЛОКАЛЬНОЙ ФУНКЦИОНАЛЬНОЙ АКТИВНОСТИ ГОЛОВНОГО МОЗГА ПРИ РЕЧЕВЫХ НАРУШЕНИЯХ У ДЕТЕЙ С ЭПИЛЕПСИЕЙ, СОПРОВОЖДАЮЩЕЙСЯ ЗАДЕРЖКОЙ ПСИХИЧЕСКОГО РАЗВИТИЯ (ПО ДАННЫМ ПОЗИТРОННО-ЭМИССИОННОЙ ТОМОГРАФИИ)CHANGES OF THE LOCAL FUNCTIONAL BRAIN ACTIVITY ASSOCIATED WITH SPEECH DISORDERS IN CHILDREN WITH EPILEPSY AND DEVELOPMENTAL DELAY (PET STUDY)ХоменкоЮ. Г.KhomenkoYu. G.

кандидат психологических наук, научный сотрудник лаборатории нейровизуализации,

197376, Санкт-Петербург, ул. Академика Павлова, д. 9

St. Petersburg

julkhom@rambler.ruКатаеваГ. В.KataevaG. V.

кандидат биологических наук, заместитель директора по научной работе,

197376, Санкт-Петербург, ул. Академика Павлова, д. 9

St. Petersburg

galina@ihb.spb.ruКоломиецВ. И.KolomiecV. I.

кандидат медицинских наук, младший научный сотрудник Центра психофизиологии аномального развития,

197376, Санкт-Петербург, ул. Академика Павлова, д. 9

St. Petersburg

val781@mail.ruИнститут мозга человека им. Н. П. Бехтеревой Российской академии наукРоссияN. P. Bechtereva Institute of the Human Brain of Russian Аcademy of SciencesRussian Federation201830012019043943Copyright © Хоменко Ю.Г., Катаева Г.В., Коломиец В.И., 20192019Хоменко Ю.Г., Катаева Г.В., Коломиец В.И.Khomenko Y.G., Kataeva G.V., Kolomiec V.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://radiag.bmoc-spb.ru/jour/article/view/340

Проведено ПЭТ-исследование церебрального метаболизма глюкозы у 73 детей с эпилепсией и задержкой психического развития (ЗПР). При нарушениях экспрессивной речи выявлено снижение скорости метаболизма глюкозы (СМГ) в верхней лобной извилине, хвостатом ядре и таламусе левого и правого полушарий. При сочетании нарушений экспрессивной и импрессивной речи значимое снижение СМГ наблюдалось в средней височной и надкраевой извилине левого полушария. Полученные результаты подтверждают, что большое значение в  развитии речевых функций имеют структуры головного мозга, обеспечивающие исполнительные функции и сложные ассоциативные процессы.

PET study of cerebral glucose metabolism was performed in 73 children with epilepsy and mental retardation. Expressive speech disorders were associated with decrease of cerebral metabolism rate of glucose (CMRglu) in the upper frontal gyrus, caudate nucleus and thalamus of the left and right hemispheres. In the group with combined expressive and impressive speech disorders the significant CMRglu reduction in the middle temporal and supramarginal gyrus of the left hemisphere was observed. The obtained results confirm that the brain structures associated with the executive functions and complex association processes have a great significance in the speech development.

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The authors declare that there are no conflicts of interest present.