ldtЛучевая диагностика и терапияDiagnostic radiology and radiotherapy2079-5343Baltic Medical Education Center10.22328/2079-5343-2019-10-2-5-14ldt-408Research ArticleРЕДАКЦИОННАЯ СТАТЬЯEDITORIALПРЕНАТАЛЬНАЯ ПРОТОННАЯ МАГНИТНО-РЕЗОНАНСНАЯ СПЕКТРОСКОПИЯ ГОЛОВНОГО МОЗГАPRENATAL PROTON MAGNETIC RESONANCE SPECTROSCOPY OF THE BRAINТрофимоваТ. Н.TrofimovaT. N.

Трофимова Татьяна Николаевна — доктор медицинских наук, профессор, руководитель НК и ОЦ «Лучевая диагностика и ядерная медицина» Института высоких медицинских технологий ФГБОУ ВПО «Санкт-Петербургский государственный университет»;

главный научный сотрудник ФГБУН «Институт мозга человека им. Н. П. Бехтеревой» Российской академии наук;

197376, Санкт-Петербург, ул. Академика Павлова, д. 9;

ХаликовА. Д.KhalikovA. D.

Халиков Азиз Джауланович — к.м.н., врач-рентгенолог, главный врач НМЦ — «Томография» клиники «Скандинавия»;

доцент НК и ОЦ «Лучевая диагностика и ядерная медицина» института высоких медицинских технологий СПбГУ

St. Petersburg

СеменоваМ. Д.SemenovaM. D.

Семенова Мария Дмитриевна — врач-рентгенолог отделения МРТ;

ассистент кафедры радиологии, хирургии и онкологии ФГБУ «РНЦРХТ им. академика А. М. Гранова» МЗ РФ

St. Petersburg

maria@sokurenko.nameБогданА. А.BogdanA. A.

St. Petersburg

ООО «НМЦ-Томография», клиника «Скандинавия»; Санкт-Петербургский государственный университет; Институт мозга человека им. Н. П. Бехтеревой Российской академии наукРоссияOOO «NMC-Tomography», «Scandinavia» clinic; St. Petersburg State University; Institute of Human Brain named after N. P. BekhterevaRussian FederationООО «НМЦ-Томография», клиника «Скандинавия»; Санкт-Петербургский государственный университетРоссияOOO «NMC-Tomography», «Scandinavia» clinic; St. Petersburg State UniversityRussian FederationИнститут мозга человека им. Н. П. Бехтеревой Российской академии наук; Российский научный центр радиологии и хирургических технологий им. акад. А. М. ГрановаРоссияInstitute of Human Brain named after N. P. Bekhtereva, Russian Academy of Sciences; Russian Research Center of Radiology and Surgical Technologies named after academic A. M. GranovRussian FederationИнститут мозга человека им. Н. П. Бехтеревой Российской академии наукРоссияInstitute of Human Brain named after N. P. Bekhtereva, Russian Academy of SciencesRussian Federation20190208201902514Copyright © Трофимова Т.Н., Халиков А.Д., Семенова М.Д., Богдан А.А., 20192019Трофимова Т.Н., Халиков А.Д., Семенова М.Д., Богдан А.А.Trofimova T.N., Khalikov A.D., Semenova M.D., Bogdan A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://radiag.bmoc-spb.ru/jour/article/view/408

В статье продемонстрирован первый российский опыт пренатальной протонной магнитно резонансной спектроскопии (1Н МРС) головного мозга, проанализированы результаты полученного исследования, оценены изменения метаболитов в зависимости от срока гестации. Нейровизуализационные методы оценки метаболизма могут играть определенную роль в диагностике и прогнозе неврологических нарушений перинатального генеза, поэтому информация о нормальных церебральных метаболических процессах крайне важна. 1Н МРС головного мозга представляет собой информативный, неинвазивный метод исследования, выполняемый комплементарно к МРТ и предоставляющий уникальную информацию о церебральном биохимическом составе. Метаболические изменения головного мозга могут предшествовать структурным, т.е. появление изменений на спектрограммах может опережать появление таковых на традиционной МРТ, а следовательно, метод может быть полезен в раннем выявлении патологии. Ранняя диагностика нарушения нормальных метаболических процессов головного мозга может быть полезна в выявлении будущих потенциальных терапевтических стратегий.

The article demonstrates the first Russian experience of prenatal proton magnetic resonance spectroscopy (1Н MRS) of the brain. The results of the study are analyzed, the metabolic changes during the gestation period is evaluated. Neuroimaging methods of assessing brain metabolism may play a role in the diagnosis and prognosis of some perinatal neurological disorders, that is why the information about normal cerebral metabolic processes is extremely important. Prenatal 1Н MRS of the brain is an informative, non invasive diagnostic method that is performed complementary to MRI and provides unique information about the cerebral biochemical composition. Brain metabolic changes may precede structural, e.g. the appearance of changes in the spectrograms may outgo the changes in traditional MRI, therefore, the method may be useful in the early detection of a pathology. Early detection of abnormal metabolic brain processes may be helpful in identifying future potential therapeutic strategies.

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The authors declare that there are no conflicts of interest present.