A rare clinical case of adult primary central nervous system neuroblastoma: a clinical case
https://doi.org/10.22328/2079-5343-2024-15-4-111-119
Abstract
Central nervous system neuroblastoma is a rare, usually metastatic (secondary) high-grade embryonal tumor, occurring in the early stage in less than 10% of cases. Generally, when malignant cerebral tumors are detected in adults, inclusion of primary neuroblastoma in the differential diagnosis naturally does not arise. The differential diagnosis consists mainly of high-grade glial tumors, metastatic lesions and cerebral lymphoma. Thus radiology, realized by multiparametric MRI mapping, is a decision making procedure. In thus publication we present a rare case of primary central nervous system neuroblastoma in a 32-year-old patient.
About the Authors
V. V. SpasennikovRussian Federation
Vladislav V. Spasennikov – Radiologist
625039, Tyumen, Melnikaite St., 75
R. S. Talybov
Russian Federation
Rustam S. Talybov – Cand. of Sci. (Med.), Radiologist, assistant of the Department of Oncology with a course of radiation diagnostics and radiation therapy
625023, Tyumen, Odesskaya St., 54
V. V. Mochalov
Russian Federation
Vadim V. Mochalov – Radiologist
625039, Tyumen, Melnikaite St., 75
V. I. Gorshkova
Russian Federation
Vladislava I. Gorshkova – Radiologist
625039, Tyumen, Melnikaite St., 75
T. N. Trofimova
Russian Federation
Tatyana N. Trofimova – Dr. of Sci. (Med.), Professor, Corresponding Member of the Russian Academy of Sciences, Professor of the radiology department and radiation medicine
197022, St. Petersburg, L’va Tolstogo St., 6–8
T. M. Kleschevnikova
Russian Federation
Tatyana M. Kleschevnikova – Head physician
625039, Tyumen, Melnikaite St., 75
References
1. Mastronuzzi A., Colafati G.S., Carai A. et al. Central Nervous System Metastasis in Neuroblastoma: From Three Decades Clinical Experience to New Considerations in the Immunotherapy Era // Cancers (Basel). 2022. Vol. 14. P. 6249. doi: 10.3390/cancers14246249.
2. Holsten T., Lubieniecki F., Spohn M. et al. Detailed Clinical and Histopathological Description of 8 Cases of Molecularly Defined CNS Neuroblastomas // J. Neuropathol Exp. Neurol. 2021. Vol. 80. P. 52–59. doi: 10.1093/jnen/nlaa128.
3. Tauziède-Espariat A., Figarella-Branger D., Métais A. et al. CNS neuroblastoma, FOXR2-activated and its mimics: a relevant panel approach for work-up and accurate diagnosis of this rare neoplasm // Acta Neuropathol Commun. 2023. Vol. 11, P. 43. doi: 10.1186/s40478-023-01536-7.
4. Talybov R., Trofimova T. N., Pavlova V. I. et al. Atypical case of glioblastoma localization: infratentorial localization (Clinical Case and the Review of the Literature) // Radiology — Practice. 2024. Vol. 1. P. 9–19. doi: 10.52560/2713-0118-2024-1-9-19.
5. Wu H., Beylerli O., Gareev I. et al. Are there reliable multiparametric MRI criteria for differential diagnosis between intracranial meningiomas and solitary intracranial dural metastases? // Oncology Letters. 2023. Vol. 26. P. 350. doi: 10.3892/ol.2023.13936.
6. Talybov R.S., Trofimova T.N. Differential diagnosis of primary lymphomas of the central nervous system according to multiparametric MRI mapping. Diagnostic radiology and radiotherapy, 2022, Vol. 13, pp. 36–49 (In Russ.). doi: 10.22328/2079-5343-2022-13-2-36-49.
7. Talibov R.S., Trofimova T.N. et al. Reliability of diffusion-weighted images and perfusion parameters in the differential diagnosis of malignant and conditionally benign intracranial formations: a single-center study. Diagnostic radiology and radiotherapy, 2023, Vol. 14, pp. 48–63 (In Russ.). doi: 10.22328/2079-5343-2023-14-2-48-63.
8. Huynh B.Q., Hung N.D., Khuong N.H., Anh N.N., Duc N.M. A rare case of a primary central nervous system neuroblastoma mimicking a trigeminal schwannoma in an adult // Radiol. Case Rep. 2023. Vol. 18. P. 2697–2703. doi: 10.1016/j.radcr.2023.05.028.
9. Beylerli O., Talybov R., Musaev E., Trofimova T. et. al. Cerebrovascular disorders in patients with malignant tumors // Brain Hemorrhages. 2024. Vol. 4. P. 1–18. doi: 10.1016/j.hest.2024.08.003.
Review
For citations:
Spasennikov V.V., Talybov R.S., Mochalov V.V., Gorshkova V.I., Trofimova T.N., Kleschevnikova T.M. A rare clinical case of adult primary central nervous system neuroblastoma: a clinical case. Diagnostic radiology and radiotherapy. 2024;15(4):111-119. (In Russ.) https://doi.org/10.22328/2079-5343-2024-15-4-111-119