Ultrasound quantitative liver steatometry in overweight patients: the possibilities of improved technique
https://doi.org/10.22328/2079-5343-2020-11-1-64-69
Abstract
Objective: to assess the state of the liver parenchyma in patients with fat overweight using the quantitative ultrasound steatometry method. Material and methods: 118 patients aged 19–75 years were examined, 52 of them men (44%) and 66 women (56%) due to a single 7 (8) stages diagnostic algorithm: questioning and complaints collecting, quality of life, clinical inspection, non-invasive bioimpedancemetry with subsequent assessment of fat mass index, ultrasound liver examination in B-mode, quantitative ultrasound steatometry with ultrasound wave attenuation coefficient evaluation, dual-energy X-ray absorptiometry in the «Whole body» mode, liver biopsy with histological microscopic specimens on SAF and NAS scales assessment. The control group consisted of 46 patients with a normal ration of fat mass and without ultrasound signs of fatty liver infiltration. Results: there were no signs of liver steatosis in 4 patients (3,4%) with a clinical picture of metabolic syndrome were detected using instrumental diagnostic methods. The sensitivity and specificity of B-mode were 60,4% and 72,8%, respectively, quantitative ultrasound steatometry — 90,7% and 92,4%, dual-energy X-ray absorptiometry in the «Whole body» mode — 88,7% and 90,1%. Conclusion: Ultrasound steatometry is an informative method for non-alcoholic fatty liver disease screening. The correlation of quantitative ultrasound diagnostics data for steatosis with a biopsy at stage S0 corresponds to r=0,87; at stage S1 r=0,69, S2 r=0,75, at stage S3 corresponds to r=0,86, which indicates the high informativeness of this method; Dual-energy X-ray absorptiometry in the «Whole body» mode can be used as an alternative to multislice computed tomography to identify components of the metabolic syndrome due to low radiation exposure.
About the Authors
D. Yu. Venidiktova
Smolensk State Medical University
Russian Federation
Russian Federation
Darya Yu. Venidiktova
Problem Scientific Research Laboratory «Diagnostic researches and miniinvasive techniques
Smolensk
A. V. Borsukov
Smolensk State Medical University
Russian Federation
Russian Federation
Alexey V. Borsukov
Problem Scientific Research Laboratory «Diagnostic researches and miniinvasive techniques
Smolensk
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For citations:
Venidiktova D.Yu., Borsukov A.V. Ultrasound quantitative liver steatometry in overweight patients: the possibilities of improved technique. Diagnostic radiology and radiotherapy. 2020;11(1):64-69. (In Russ.) https://doi.org/10.22328/2079-5343-2020-11-1-64-69
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