Multimodal neuroimaging verification of ganglioglioma associated with neuronal heterotopy in an adult patient without epileps
https://doi.org/10.22328/2079-5343-2022-13-1-21-29
Abstract
Gangliogliomas are known to be rare and mainly slow-growing benign primary central nervous system tumors, most frequently occurring in children and young adults. They are the most common epilepsy-associated tumors, which frequent location is the temporal lobe. Surgery often seems to be the best approach in controlling seizures in such patients. This paper deals with a rare case of ganglioglioma in a young adult patient with a temporal lobe tumor associated with neuronal heterotopy of white matter, but without epilepsy. Long-term dynamic observation including in-depth clinical, electroencephalographic, radiologic, and postsurgical histologic examination confirmed the documented neoplastic process without any manifestation of seizures over ten years. Surgical intervention was based on the results of a multimodal radiological examination, which demonstrated the presence of neoplasm in the structure of the pathological substrate of unclear etiology.
About the Authors
V. S. Khalilov
Pirogov Russian National Research Medical University;
Federal Research and Clinical Center for Children and Adolescents
Russian Federation
Russian Federation
PhD, Associate professor at the Department of Neurology, Neurosurgery and Medical Genetics named after academician L. O. Badalyan, Faculty of Pediatrics, Ostrovitjanova str. 1;
Doctor of the MRI Department, Moscow, Moskvorechye str. 20
A. N. Kislyakov
Morozov Children Clinical Hospital
Russian Federation
Russian Federation
Head of the Pathology Department,
119049, 4th Dobrininskiypereulok, 1/9, Moscow;
A. A. Kholin
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
MD, PhD, Professor at the Department of Neurology, Neurosurgery and Medical Genetics named after academician L. O. Badalyan, Faculty of Pediatrics,
Moscow, Ostrovitjanova str. 1
Kh. S. Gazdieva
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
post-graduate Student, Chair of the Department of Neurology, Neurosurgery and Medical Genetics named after academician L. O. Badalyan, Faculty of Pediatrics,
Moscow, Ostrovitjanova str. 1
K. I. Panova
Health center 4
Latvia
Latvia
radiologist the department of radiology,
Riga
N. N. Zavadenko
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Doctor of Science, professor, Head of the Department of Neurology, Neurosurgery and Medical Genetics named after academician L. O. Badalyan, Faculty of Pediatrics,
Moscow, Ostrovitjanova str. 1
K. Kobow
University Hospital Erlangen
Germany
Germany
PhD professor (assistant) Institute of Neuropathology,
Schwabachanlage 14 Erlangen
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Review
For citations:
Khalilov V.S., Kislyakov A.N., Kholin A.A., Gazdieva Kh.S., Panova K.I., Zavadenko N.N., Kobow K. Multimodal neuroimaging verification of ganglioglioma associated with neuronal heterotopy in an adult patient without epileps. Diagnostic radiology and radiotherapy. 2022;13(1):21-29. (In Russ.) https://doi.org/10.22328/2079-5343-2022-13-1-21-29
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