Neuroinfection of mixed etiology: modern diagnosis of urgent conditions in children: а review

Introduction: Recently, the number of mixed infectious lesions of the nervous system (NS) among children has been increasing. This pathology is characterized by a severe course and rapid development of urgent conditions.

Objective: To demonstrate a universal diagnostic algorithm using clinical laboratory and neuroimaging research methods in the conditions of a child’s stay in the intensive care unit.

Materials and methods: We present our own clinical cases of the use of modern laboratory and instrumental diagnostic methods, especially neurosonography (NSG), computed tomography (CT) and multiparametric magnetic resonance imaging (MRI).

Results: These methods made it possible to make a correct diagnosis in a short time, determine the degree of morphofunctional disorders on the part of the NS, the presence of complications, and also to assume the outcome of the disease.

Discussion: Central NS infections of mixed etiology are characterized by polymorphism of the clinical picture and rapid development of urgent conditions. This requires early diagnosis using laboratory and instrumental research methods to prescribe adequate therapy and predict the outcome of the disease.

Conclusion: Timely diagnosis and early start of treatment of NS mixed infection and possible complications helps to improve the outcomes of the disease.

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