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THE ABILITY OF 3D-SSP ANALYSIS OF 18F-FDG PET DATA IN THE DIAGNOSIS OF ALZHEIMER’S DISEASE

https://doi.org/10.22328/2079-5343-2016-2-47-51

Abstract

The technique of 3D-SSP is widely used in the world in the diagnosis of neurological diseases. The purpose of the study was to investigate the metabolic activity of different brain structures in patients with mild cognitive deficiency and Alzheimer’s disease. 81 patients were examined, 31 of them with mild cognitive deficiency and 41 with Alzheimer’s disease. Identified thresholds metabolic activity of the active values of Z-bills in the association cortex of the temporal lobes, equal to 1,54. In this method, the sensitivity was 87,8%, specificity - 90,3%. Thus, the set values of Z-accounts to use the software 3D-SSP in patients with cognitive impairment, allowing high-precision semi-quantitatively measure changes in glucose metabolism in different brain structures.

About the Authors

M. V. Artemov
Russian scientific center of radiology and surgical technologies
Russian Federation


A. A. Stanzhevsky
Russian scientific center of radiology and surgical technologies
Russian Federation


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Review

For citations:


Artemov M.V., Stanzhevsky A.A. THE ABILITY OF 3D-SSP ANALYSIS OF 18F-FDG PET DATA IN THE DIAGNOSIS OF ALZHEIMER’S DISEASE. Diagnostic radiology and radiotherapy. 2016;(2):47-51. (In Russ.) https://doi.org/10.22328/2079-5343-2016-2-47-51

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