PET-STUDY OF THE LOCAL CEREBRAL GLUCOSE METABOLISM RATE IN CHILDREN SUFFERED FROM EPILEPSY AND DEVELOPMENTAL DELAY
Abstract
The analysis of the PET images with 18F-fluorodezoxyglucose (18F-FDG) in children suffered from epilepsy with or without co-morbid developmental delay was performed. Decrease of the local glucose metabolic rate was revealed in superior frontal gyrus and angular gyrus bilaterally; in parahyppocampal, submarginal and inferior temporal gyri in the left hemisphere. It was also revealed that the local glucose metabolic rate in several cortical zones depends on the age of children. It is suggested that the revealed peculiarities of the glucose metabolism are related to the maturation deceleration of the cerebral cortex in epilepsy and developmental delay.
About the Authors
Y. G. Khomenko
N.P. Bechtereva Institute of the Human Brain, Russian Academy of Sciences
Russian Federation
Russian Federation
G. V. Kataeva
N.P. Bechtereva Institute of the Human Brain, Russian Academy of Sciences
Russian Federation
Russian Federation
V. I. Semivolos
N.P. Bechtereva Institute of the Human Brain, Russian Academy of Sciences
Russian Federation
Russian Federation
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Review
For citations:
Khomenko Y.G., Kataeva G.V., Semivolos V.I. PET-STUDY OF THE LOCAL CEREBRAL GLUCOSE METABOLISM RATE IN CHILDREN SUFFERED FROM EPILEPSY AND DEVELOPMENTAL DELAY. Diagnostic radiology and radiotherapy. 2015;(1):45-49. (In Russ.)
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