DCE-MRI IN BRAIN TUMOR DIAGNOSIS
https://doi.org/10.22328/2079-5343-2017-1-13-22
Abstract
In recent years there has been intensive development and clinical implementation of new techniques of noninvasive radiology diagnostics that measure characteristics of blood flow in tumors, which is one of the most important mechanisms of tumor growth and contribute to the ability of tumors to respond to ongoing systemic therapy. Awareness of clinicians about the features of tumor perfusion characteristics, in this context of brain tumors, is an important condition for optimizing the results of the use of drugs aimed at suppression of tumor neoangiogenesis. Established tissue perfusion CT and MRI studies based on the assessment of speed and volume of blood flow, and mean transit time. However, clinicians are not completely satisfied with the results of these technologies. Nowadays promising (in the sense of expanding the diagnostic capabilities of the MRI) is the method of MR dynamic contrast enhancement, which provides objective information on the permeability degree of capillary walls and thereby reflects the pathological transformation at the level of the blood-brain barrier.
About the Author
E. A. NechipayRussian Federation
Moscow
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Review
For citations:
Nechipay E.A. DCE-MRI IN BRAIN TUMOR DIAGNOSIS. Diagnostic radiology and radiotherapy. 2017;(1):13-22. (In Russ.) https://doi.org/10.22328/2079-5343-2017-1-13-22