EXPERIENCE OF SENTINEL LYMPHADENECTOMY GUIDED BY NUCLEAR IMAGING IN PATIENTS WITH OROPHARYNGEAL MALIGNANCIES

The excision of sentinel lymph nodes has a growing relevance in the diagnostics of oral and oropharyngeal cancer in case of N0. The validity of sentinel node biopsy (SNB) was examined as single surgical staging tool. Within the framework of a multi-modality treatment scheme, SNB without elective neck dissection performed during surgery of the primary tumor in 70 previously untreated patients. Control of accuracy took place by observation of manifestation of neck node metastases in 45 patients who had not been postoperatively irradiated. 94% of sentinel nodes could be excised; nine patients (13%) had positive nodes and were undergone radical neck lymph nodes dissection. There were 2 neck lymph node metastases in the context of second primaries, all other patients remained regionally unconspicious (median observation time: 26 months). As staging tool assessing T1-3 N0 tumors, SNB could lead to a considerable reduction of the number of elective neck dissections. it could be integrated well into a multi-modality treatment scheme.

сторожевые лимфатические узлы, хирургическое лечение, карцинома ротоглотки, сцинтиграфия сторожевых узлов, ФДГ-ПЭТ, sentinel lymph node biopsy, mouth neoplasms, head and neck neoplasms, sentinel lymph node scintigraphy, FDG-PET

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