CHANGES OF THE LOCAL FUNCTIONAL BRAIN ACTIVITY ASSOCIATED WITH SPEECH DISORDERS IN CHILDREN WITH EPILEPSY AND DEVELOPMENTAL DELAY (PET STUDY)
https://doi.org/10.22328/2079-5343-2018-4-39-43
Abstract
PET study of cerebral glucose metabolism was performed in 73 children with epilepsy and mental retardation. Expressive speech disorders were associated with decrease of cerebral metabolism rate of glucose (CMRglu) in the upper frontal gyrus, caudate nucleus and thalamus of the left and right hemispheres. In the group with combined expressive and impressive speech disorders the significant CMRglu reduction in the middle temporal and supramarginal gyrus of the left hemisphere was observed. The obtained results confirm that the brain structures associated with the executive functions and complex association processes have a great significance in the speech development.
About the Authors
Yu. G. Khomenko
N. P. Bechtereva Institute of the Human Brain of Russian Аcademy of Sciences
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
G. V. Kataeva
N. P. Bechtereva Institute of the Human Brain of Russian Аcademy of Sciences
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
V. I. Kolomiec
N. P. Bechtereva Institute of the Human Brain of Russian Аcademy of Sciences
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
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Review
For citations:
Khomenko Yu.G., Kataeva G.V., Kolomiec V.I. CHANGES OF THE LOCAL FUNCTIONAL BRAIN ACTIVITY ASSOCIATED WITH SPEECH DISORDERS IN CHILDREN WITH EPILEPSY AND DEVELOPMENTAL DELAY (PET STUDY). Diagnostic radiology and radiotherapy. 2018;(4):39-43. (In Russ.) https://doi.org/10.22328/2079-5343-2018-4-39-43
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