RESPIRATORY SYSTEM INVOLVEMENT IN PATIENTS WITH ANTIPHOSPHOLIPID SYNDROME

In the early 1980^s the definition of antiphospholipid syndrome (APS) was firstly formulated as a rare form of antibodies induced thrombophilia, which clinical features were thrombosis and obstetrical pathology. However, according to the results of the constant study of the pathogenetic mechanisms of APS the role of antiphospholipid antibodies has proved in a wide range of clinical manifestations, which greatly expanded the understanding of the syndrome. For example, for the beginning and during the disease APS characterized by various lesions of the respiratory system. The most frequent complications are thromboembolism, thrombosis in situ and pulmonary hypertension. Less common in the literature describe the acute respiratory distress syndrome adults, alveolar hemorrhage, pulmonary capillary, postpartum syndrome. There are descriptions of combined observations APS and fibrosing alveolitis, however, now a clear link between the pathology has not been proved. The problem of the study of lung disease in patients with APS remains relevant in connection with the constant life-threatening currents and frequent deaths. Early diagnosis and early aggressive treatment, which is strongly depend on the lesion, is necessary. This review provides information about the features of the flow, diagnosis and treatment of pleuropulmonary manifestations of APS.

антифосфолипидный синдром, поражения дыхательной системы, принципы диагностики, лучевые методы диагностики, постпроцессинговая обработка, цветовое картирование, antiphospholipid antibody syndrome, respiratory system involvement, X-ray methods, post-processing, color mapping

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